PPARG Antikörper
Kurzübersicht für PPARG Antikörper (ABIN7005461)
Target
Alle PPARG Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Produktmerkmale
- Monoclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse PPARgamma
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Isotyp
- IgG
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Applikationshinweise
- IHC 1:300-1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
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Andere Bezeichnung
- PPARG
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Hintergrund
- This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
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UniProt
- P37238, O88275
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Pathways
- MAPK Signalweg, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
Target
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