Iba1 Antikörper
Kurzübersicht für Iba1 Antikörper (ABIN7249968)
Target
Alle Iba1 (IBA1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Produktmerkmale
- Monoclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse IBA-1
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Isotyp
- IgG
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Applikationshinweise
- IHC 1:200-1:800
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.4 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))
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Andere Bezeichnung
- AIF1
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Hintergrund
- This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene.Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
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UniProt
- O70200
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Pathways
- Smooth Muscle Cell Migration
Target
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