TEK
Reaktivität: Human
WB, ELISA
Wirt: Maus
Monoclonal
5G6
unconjugated
Applikationshinweise
IHC 1:200-1:800
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
470 μg/mL
Buffer
PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
TEK
(TEK Tyrosine Kinase, Endothelial (TEK))
Andere Bezeichnung
TEK
Hintergrund
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.