Cullin 4A Antikörper
Kurzübersicht für Cullin 4A Antikörper (ABIN7247885)
Target
Alle Cullin 4A (CUL4A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Antigen affinity purification
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Immunogen
- Synthetic peptide of human CUL4A
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Isotyp
- IgG
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anti-Cullin 4A (CUL4A) antibody
CUL4A Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 4A (CUL4A) (AA 1-759) antibodyCUL4A Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 4A (CUL4A) (AA 31-60), (N-Term) antibodyCUL4A Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB33954 unconjugated
anti-Cullin 4A (CUL4A) (AA 1-100) antibodyCUL4A Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Cullin 4A (CUL4A) (AA 1-100) antibodyCUL4A Reaktivität: Human ELISA, IF Wirt: Maus Monoclonal 3H3 unconjugated
anti-Cullin 4A (CUL4A) (AA 1-759) antibodyCUL4A Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Cullin 4A (CUL4A) antibodyCUL4A Reaktivität: Human, Maus, Ratte WB, IHC, IF, IC Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 4A (CUL4A) (Middle Region) antibodyCUL4A Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Hund, Rind (Kuh), Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 4A (CUL4A) (AA 1-61) antibodyCUL4A Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 4A (CUL4A) (N-Term) antibodyCUL4A Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.62 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cullin 4A (CUL4A)
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Andere Bezeichnung
- CUL4A
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Hintergrund
- Cullin proteins assemble a large number of RING E3 ubiquitin ligases,participating in the proteolysis through the ubiquitin-proteasome pathway. Two cullin 4 (CUL4) proteins,CUL4A (87 kDa) and CUL4B(104 kDa),have been identified. The two CUL4 sequences are 83 % identical. They target certain proteins for degradation by binding protein DDB1 to form a CUL4-DDB1 ubiquitin ligase complex with DDB. They form two individual E3 ligases,DDB1-CUL4ADDB2 and DDB1-CUL4BDDB2 in this process. CUL4A appeared in both the nucleus and the cytosol,suggesting a more complex mechanism for entering the nucleus. CUL4B is localized in the nucleus and facilitates the transfer of DDB1 into the nucleus independently of DDB2.
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Molekulargewicht
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Observed_MW: Refer to figures
Calculated_MW: 88 kDa
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UniProt
- Q13619
Target
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