IDO2 Antikörper
Kurzübersicht für IDO2 Antikörper (ABIN7245806)
Target
Alle IDO2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Produktmerkmale
- Polyclonal Antibody
-
Aufreinigung
- Antigen affinity purification
-
Immunogen
- Full length fusion protein
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))
-
Andere Bezeichnung
- IDO2
-
Hintergrund
- INDOL1 is also known as IDO2 (indoleamine 2,3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2,3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1.
-
Molekulargewicht
-
Observed_MW: Refer to figures
Calculated_MW: 45 kDa
-
UniProt
- Q6ZQW0
Target
-