Der Kaninchen Polyklonal Anti-MYSM1-Antikörper wurde für ELISA, WB und IHC validiert. Er ist geeignet, MYSM1 in Proben von Human und Maus zu detektieren.
MYSM1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.7 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
MYSM1
(Myb-Like, SWIRM and MPN Domains 1 (MYSM1))
Andere Bezeichnung
MYSM1
Hintergrund
Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.