LRP5 Antikörper

Produktnummer ABIN7242257

Dieser Anti-LRP5-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von LRP5 in IHC und ELISA. Geeignet für Human und Maus.

Kurzübersicht für LRP5 Antikörper (ABIN7242257)

Target: LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRP5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-LRP5 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human LRP5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu LRP5

Target: LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

Andere Bezeichnung: LRP5

Hintergrund: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.

NCBI Accession: NP_002326

UniProt: O75197

Pathways: WNT Signalweg, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation