RRM1 Antikörper
Kurzübersicht für RRM1 Antikörper (ABIN7240211)
Target
Alle RRM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Produktmerkmale
- Polyclonal Antibody
-
Aufreinigung
- Affinity purification
-
Immunogen
- Recombinant protein of human RRM1
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-1:2000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.3 mg/mL
-
Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- RRM1 (Ribonucleotide Reductase M1 (RRM1))
-
Andere Bezeichnung
- RRM1
-
Hintergrund
- This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.
-
Molekulargewicht
- 90 kDa
-
UniProt
- P23921
-
Pathways
- Positive Regulation of Endopeptidase Activity
Target
-