HSD17B1 Antikörper
Kurzübersicht für HSD17B1 Antikörper (ABIN7239050)
Target
Alle HSD17B1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Synthetic peptide of human HSD17B1
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Isotyp
- IgG
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anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (AA 189-285) antibody
HSD17B1 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 2E5 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (AA 29-43), (N-Term) antibodyHSD17B1 Reaktivität: Human, Ratte WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (AA 29-43) antibodyHSD17B1 Reaktivität: Human, Maus, Ratte WB, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) antibodyHSD17B1 Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (AA 4-289) antibodyHSD17B1 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (AA 268-328) antibodyHSD17B1 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (AA 21-120) antibodyHSD17B1 Reaktivität: Human, Maus WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (N-Term) antibodyHSD17B1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Meerschweinchen, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (N-Term) antibodyHSD17B1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (C-Term) antibodyHSD17B1 Reaktivität: Human WB, IHC, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.9 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))
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Andere Bezeichnung
- HSD17B1
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Hintergrund
- Hydroxysteroid (17-beta) dehydrogenase 1 catalyzes the final step in the formation of estradiol and testosterone from estrone and androstenedione, respectively. Ovarian granulosa cells and breast tissue both express HSD17B1. Other tissues that express HSD17B1 include testis, placenta, uterus, prostate and adipose tissue. HSD17B1 functions as a homodimer and prefers NADP(H) over NAD(H) for oxidation and reduction. The gene encoding human HSD17B1 maps to chromosome 17q12-q21. The importance of HSD17B1 to estradiol production suggests the specific inhibition of HSD17B1 may aid in breast cancer therapy.
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Molekulargewicht
- 35 kDa
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NCBI Accession
- NP_000404
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UniProt
- P14061
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Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis
Target
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