HSD17B1 Antikörper (N-Term)
Kurzübersicht für HSD17B1 Antikörper (N-Term) (ABIN2776958)
Target
Alle HSD17B1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- HSD17B1 Antibody - N-terminal region
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Sequenz
- MARTVVLITG CSSGIGLHLA VRLASDPSQS FKVYATLRDL KTQGRLWEAA
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against HSD17B1. It was validated on Western Blot and immunohistochemistry.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human HSD17B1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8102873
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Association between endometriosis and genetic polymorphisms of the estradiol-synthesizing enzyme genes HSD17B1 and CYP19." in: Human reproduction (Oxford, England), Vol. 20, Issue 4, pp. 974-8, (2005) (PubMed).
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- HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))
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Andere Bezeichnung
- HSD17B1
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Hintergrund
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Background Information: HSD17B1 is favors the reduction of estrogens and androgens. It also has 20-alpha-HSD activity. It uses preferentially NADH.
Gene Name: Hydroxysteroid (17-beta) dehydrogenase 1
Alternative Symbols: E2DH, HSD17, EDHB17, EDH17B2, SDR28C1, 17-beta-HSD, 20-alpha-HSD
Protein Name: Estradiol 17-beta-dehydrogenase 1
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Molekulargewicht
- 36kDa
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Gen-ID
- 3292
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NCBI Accession
- NP_000404
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UniProt
- P14061
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Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis
Target
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