HMGCS1 Antikörper
Kurzübersicht für HMGCS1 Antikörper (ABIN7239032)
Target
Alle HMGCS1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Synthetic peptide of human HMGCS1
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Isotyp
- IgG
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anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 1-238) antibody
HMGCS1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 293-467) antibodyHMGCS1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 290-317) antibodyHMGCS1 Reaktivität: Human, Maus WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB20146 unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 241-520) antibodyHMGCS1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 360-520) antibodyHMGCS1 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 442-470), (C-Term) antibodyHMGCS1 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB20147 unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (Internal Region) antibodyHMGCS1 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 251-300) antibodyHMGCS1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Schwein, Hamster, Xenopus laevis WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) antibodyHMGCS1 Reaktivität: Human, Maus, Ratte IF Wirt: Kaninchen Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 1-520) antibodyHMGCS1 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.4 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- HMGCS1 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1))
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Andere Bezeichnung
- HMGCS1
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Hintergrund
- HMG-CoA Synthase exists as both a mitochondrial (mHMGCS) and cytoplasmic (cHMGCS) enzyme that condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. The HMG-CoA produced by cHMGCS is transformed into mevalonate by HMG-CoA reductase, which starts isoprenoid biosynthesis. End products of the isoprenoid pathway include cholesterol, ubiquinone, dolichol, isopentenyl adenosine and farnesyl groups. mHMGCS, together with HMG-CoA Lyase, is responsible for ketone body biosynthesis. mHMGCS is expressed in liver and kidney. Fasting, cAMP and fatty acids increase the level of transcription of mHMGCS, while feeding and insulin repress it. A regulatory element within the mHMGCS promoter confers transcriptional regulation by PPAR, RXR, COUP-TF and HNF-4.
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Molekulargewicht
- 57 kDa
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NCBI Accession
- NP_001091742
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UniProt
- Q01581
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Pathways
- Regulation of Lipid Metabolism by PPARalpha
Target
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