SMG8 Antikörper
Kurzübersicht für SMG8 Antikörper (ABIN7238174)
Target
Alle SMG8 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Produktmerkmale
- Polyclonal Antibody
-
Aufreinigung
- Affinity purification
-
Immunogen
- Synthetic peptide of human SMG8
-
Isotyp
- IgG
-
-
anti-Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8) (AA 575-624) antibody
SMG8 Reaktivität: Human, Maus, Rind (Kuh), Pferd, Kaninchen, Schwein, Ratte, Hund, Meerschweinchen, Fledermaus, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8) (Middle Region) antibodySMG8 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8) (Middle Region) antibodySMG8 Reaktivität: Human, Maus, Rind (Kuh), Pferd, Kaninchen, Ratte, Hund, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
-
-
Applikationshinweise
- IHC 1:25-1:100
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.3 mg/mL
-
Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- SMG8 (Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
-
Andere Bezeichnung
- SMG8
-
Hintergrund
- Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity.
-
NCBI Accession
- NP_060619
-
UniProt
- Q8ND04
Target
-
