5DI antikoerper, TXDI1 antikoerper, ITDI1 antikoerper, D1 antikoerper, DIOI antikoerper, Deio1 antikoerper, cb685 antikoerper, zgc:92323 antikoerper, iodothyronine deiodinase 1 antikoerper, type I iodothyronine deiodinase-like antikoerper, deiodinase, iodothyronine, type I antikoerper, deiodinase, iodothyronine type 1 L homeolog antikoerper, DIO1 antikoerper, LOC100231867 antikoerper, Dio1 antikoerper, dio1.L antikoerper, dio1 antikoerper
Hintergrund
Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms.