DIO1 Antikörper (N-Term)

Produktnummer ABIN390946

Produktdetails anti-DIO1 Antikörper

Target: DIO1 (Deiodinase, Iodothyronine, Type I (DIO1))

Bindungsspezifität: AA 30-57, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DIO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DIO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-57 amino acids from the N-terminal region of human DIO1.

Klon: RB21147

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu DIO1

Target: DIO1 (Deiodinase, Iodothyronine, Type I (DIO1))

Andere Bezeichnung: DIO1 (DIO1 Produkte)

Synonyme: 5DI antikoerper, TXDI1 antikoerper, ITDI1 antikoerper, D1 antikoerper, DIOI antikoerper, Deio1 antikoerper, cb685 antikoerper, zgc:92323 antikoerper, iodothyronine deiodinase 1 antikoerper, type I iodothyronine deiodinase-like antikoerper, deiodinase, iodothyronine, type I antikoerper, deiodinase, iodothyronine type 1 L homeolog antikoerper, DIO1 antikoerper, LOC100231867 antikoerper, Dio1 antikoerper, dio1.L antikoerper, dio1 antikoerper

Hintergrund: DIO1 is a thiol-requiring propylthiouracil-sensitive oxidoreductase. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It also degrades both hormones by inner ring deiodination (IRD).

Molekulargewicht: 28924

Gen-ID: 1733

NCBI Accession: NP_000783, NP_001034804, NP_001034805, NP_998758

UniProt: P49895

Pathways: Hormone Activity