PRMT7 Antikörper
Kurzübersicht für PRMT7 Antikörper (ABIN7235467)
Target
Alle PRMT7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein of human PRMT7
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))
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Andere Bezeichnung
- PRMT7
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Hintergrund
- Protein arginine methyltransferase 7is aproteinthat in humans is encoded by thePRMT7gene.Argininemethylationis an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, usingS-adenosylmethionine(AdoMet) as the methyl donor. Arginine methylation is implicated insignal transduction, RNA transport, andRNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT).
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Molekulargewicht
- 78 kDa
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UniProt
- Q9NVM4
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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