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ErbB2/Her2 Antikörper (AA 376-578)

Dieses Anti-ErbB2/Her2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ErbB2/Her2 in WB, IHC, IP und ICC. Geeignet für Human.
Produktnummer ABIN7426373

Kurzübersicht für ErbB2/Her2 Antikörper (AA 376-578) (ABIN7426373)

Target

Alle ErbB2/Her2 Antikörper anzeigen
ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Reaktivität

  • 457
  • 129
  • 122
  • 33
  • 8
  • 5
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 301
  • 172
  • 10
  • 6
  • 3
  • 2
  • 2
  • 1
Maus

Klonalität

  • 295
  • 197
  • 3
Monoklonal

Konjugat

  • 304
  • 25
  • 22
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 7
  • 7
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Dieser ErbB2/Her2 Antikörper ist unkonjugiert

Applikation

  • 316
  • 141
  • 125
  • 111
  • 102
  • 93
  • 80
  • 74
  • 61
  • 54
  • 46
  • 30
  • 12
  • 9
  • 8
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Klon

C16
  • Bindungsspezifität

    • 32
    • 30
    • 26
    • 25
    • 25
    • 24
    • 17
    • 17
    • 15
    • 13
    • 13
    • 10
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    AA 376-578

    Verwendungszweck

    Monoclonal Antibody to Receptor Tyrosine Protein Kinase erbB-2 (ErbB2)

    Spezifität

    The antibody is a mouse monoclonal antibody raised against ErbB2. It has been selected for its ability to recognize ErbB2 in immunohistochemical staining and western blotting.

    Aufreinigung

    Protein A + Protein G affinity chromatography

    Immunogen

    Recombinant Receptor Tyrosine Protein Kinase erbB-2 (ErbB2) corresdonding to Phe376~Gly578 with N-terminal His and GST Tag

    Isotyp

    IgG2b kappa
  • Applikationshinweise

    Western blotting: 0.01-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

    Kommentare

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

    Haltbarkeit

    24 months
  • Target

    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

    Andere Bezeichnung

    ErbB2

    Hintergrund

    CD340, EGFR2, HER-2/neu, HER2, NEU, MLN 19, NGL, TKR1, p185, Epidermal Growth Factor Receptor 2, V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog

    UniProt

    P04626

    Pathways

    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Skeletal Muscle Fiber Development
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