ErbB2/Her2 Antikörper (AA 23-372)

Produktnummer ABIN7428701

Der Maus Monoklonal Anti-ErbB2/Her2-Antikörper wurde für WB, IHC, IP und ICC validiert. Er ist geeignet, ErbB2/Her2 in Proben von Human zu detektieren.

Kurzübersicht für ErbB2/Her2 Antikörper (AA 23-372) (ABIN7428701)

Target: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ErbB2/Her2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Klon: C3

Produktdetails anti-ErbB2/Her2 Antikörper

Bindungsspezifität: AA 23-372

Verwendungszweck: Monoclonal Antibody to Receptor Tyrosine Protein Kinase erbB-2 (ErbB2)

Spezifität: The antibody is a mouse monoclonal antibody raised against ErbB2. It has been selected for its ability to recognize ErbB2 in immunohistochemical staining and western blotting.

Aufreinigung: Protein A + Protein G affinity chromatography

Immunogen: Recombinant Receptor Tyrosine Protein Kinase erbB-2 (ErbB2) corresdonding to Thr23~Gly372 with N-terminal His Tag

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blotting: 0.5-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Kommentare:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 24 months

Details zu ErbB2/Her2

Target: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Andere Bezeichnung: ErbB2

Hintergrund: CD340, EGFR2, HER-2/neu, HER2, NEU, MLN 19, NGL, TKR1, p185, Epidermal Growth Factor Receptor 2, V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog

UniProt: P04626

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Skeletal Muscle Fiber Development