alpha Tubulin Antikörper (C-Term) (Biotin)

Produktnummer ABIN6992214

Dieses Anti-alpha Tubulin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von alpha Tubulin in WB und ELISA. Geeignet für Human, Maus, Ratte, Huhn, Zebrafisch (Danio rerio) und Kaninchen.

Kurzübersicht für alpha Tubulin Antikörper (C-Term) (Biotin) (ABIN6992214)

Target: alpha Tubulin (TUBA1)

Reaktivität: Human, Maus, Ratte, Huhn, Zebrafisch (Danio rerio), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser alpha Tubulin Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-alpha Tubulin Antikörper (Biotin)

Bindungsspezifität: C-Term

Spezifität: Biotin-Alpha-tubulin antibody is human, mouse, rat, rabbit, chicken, and zebrafish reactive.

Aufreinigung: Biotin-Alpha-tubulin antibody is affinity chromatography purified via peptide column.

Immunogen: Biotin-Alpha-tubulin antibody was raised against an 18 amino acid peptide near the carboxy terminus of human alpha-tubulin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Biotin-Alpha-tubulin antibody can be used for detection of alpha-tubulin by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human, mouse, and rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Biotin-Alpha-tubulin antibody is supplied in PBS containing 1 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Biotin-Alpha-tubulin antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu alpha Tubulin

Target: alpha Tubulin (TUBA1)

Andere Bezeichnung: Alpha-tubulin

Hintergrund: Alpha-tubulin belongs to the tubulin superfamily, which is composed of six distinct families. Along with beta-tubulins, alpha-tubulins are the major components of microtubules. These microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Alpha- and beta-tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter (reviewed in 1). Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha-tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase (2). Another post-translational modification of detyrosinated alpha-tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle (3). Like GAPDH and ?-Actin, this antibody makes an excellent loading control in immunoblots.

Molekulargewicht: Predicted: 50 kDa

Observed: 55 kDa

Gen-ID: 7846

UniProt: Q71U36

Pathways: Microtubule Dynamics