C9ORF72 Antikörper (C-Term)

Produktnummer ABIN6992180

Der Kaninchen Polyklonal Anti-C9ORF72-Antikörper wurde für WB, ELISA und ICC validiert. Er ist geeignet, C9ORF72 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für C9ORF72 Antikörper (C-Term) (ABIN6992180)

Target: C9ORF72 (Chromosome 9 Open Reading Frame 72 (C9ORF72))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C9ORF72 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Produktdetails anti-C9ORF72 Antikörper

Bindungsspezifität: AA 400-450, C-Term

Spezifität: ALSFTD antibody is human, mouse and rat reactive. At least two isoforms are known to exist.

Aufreinigung: ALSFTD Antibody is affinity chromatography purified via peptide column.

Immunogen: ALSFTD antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human ALSFTD. The immunogen is located within amino acids 400 - 450 of ALSFTD.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ALSFTD antibody can be used for the detection of ALSFTD by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry at 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ALSFTD Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ALSFTD antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu C9ORF72

Target: C9ORF72 (Chromosome 9 Open Reading Frame 72 (C9ORF72))

Andere Bezeichnung: ALSFTD

Hintergrund: ALSFTD (C9orf72) is considered to play a role in gender determination (1). Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG (2). Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster (3,4).

Molekulargewicht: Predicted: 53 kDa

Observed: 52 kDa

Gen-ID: 203228

NCBI Accession: NP_060795

UniProt: Q96LT7