PMEPA1 Antikörper (AA 160-210)

Produktnummer ABIN6992158

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PMEPA1 in WB, ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für PMEPA1 Antikörper (AA 160-210) (ABIN6992158)

Target: PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PMEPA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PMEPA1 Antikörper

Bindungsspezifität: AA 160-210

Spezifität: PMEPA1 antibody is human, mouse and rat reactive. At least four isoforms are known to exist, this antibody will detect all of the isoforms.

Aufreinigung: PMEPA1 antibody is affinity chromatography purified via peptide column.

Immunogen: PMEPA1 antibody was raised against a 16 amino acid peptide near the center of human PMEPA1. The immunogen is located within amino acids 160 - 210 of PMEPA1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PMEPA1 antibody can be used for detection of PMEPA1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PMEPA1 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PMEPA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu PMEPA1

Target: PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

Andere Bezeichnung: PMEPA1

Hintergrund: The prostate transmembrane protein, androgen induced 1 (PMEPA1) protein is a transmembrane protein that contains a Smad interacting motif (SIM) (1,2). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins (3). Overexpression of this gene may play a role in multiple types of cancer (2,4).

Molekulargewicht: Predicted: 26, 28, 32 kDa

Observed: 27 kDa

Gen-ID: 56937

NCBI Accession: NP_064567

UniProt: Q969W9

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway