MEK1/2 Antikörper (AA 240-290)

Produktnummer ABIN6992146

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MEK1/2 in WB, ELISA, IF und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für MEK1/2 Antikörper (AA 240-290) (ABIN6992146)

Target: MEK1/2 (MAP2K1/2) (Mitogen-Activated Protein Kinase Kinase 1/2 (MAP2K1/2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEK1/2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MEK1/2 Antikörper

Bindungsspezifität: AA 240-290

Spezifität: MEK1/2 antibody is human, mouse, and rat reactive. This antibody detects both MEK1 and MEK2.

Aufreinigung: MEK1/2 antibody is affinity chromatography purified via peptide column.

Immunogen: MEK1/2 antibody was raised against a 15 amino acid peptide near the center of human MEK1. The immunogen is located within amino acids 240 - 290 of MEK1/2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: MEK1/2 antibody can be used for detection of MEK1/2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: MEK1/2 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: MEK1/2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu MEK1/2

Target: MEK1/2 (MAP2K1/2) (Mitogen-Activated Protein Kinase Kinase 1/2 (MAP2K1/2))

Andere Bezeichnung: MEK1/2

Hintergrund: The mitogen-activated protein kinase kinase 1 (MAP2K1, also known as MEK1) and the highly homologous MEK2 are members of the dual specificity protein kinase family (1). MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals (2). MEK1 lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, MEK1 is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development (2).

Molekulargewicht: Predicted: 43 kDa

Observed: 44 kDa

Gen-ID: 5604

NCBI Accession: NP_002746

UniProt: Q0VD16