C2CD3 Antikörper (AA 1490-1540)

Produktnummer ABIN6992132

Der Kaninchen Polyklonal anti-C2CD3 Antikörper wird verwendet zum Nachweis von C2CD3 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für C2CD3 Antikörper (AA 1490-1540) (ABIN6992132)

Target: C2CD3 (C2 Calcium-Dependent Domain Containing 3 (C2CD3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C2CD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-C2CD3 Antikörper

Bindungsspezifität: AA 1490-1540

Spezifität: C2CD3 antibody is human, mouse and rat reactive.

Aufreinigung: C2CD3 antibody is affinity chromatography purified via peptide column.

Immunogen: C2CD3 antibody was raised against an 18 amino acid peptide near the center of human C2CD3. The immunogen is located within amino acids 1490 - 1540 of C2CD3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: C2CD3 antibody can be used for detection of C2CD3 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: C2CD3 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: C2CD3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu C2CD3

Target: C2CD3 (C2 Calcium-Dependent Domain Containing 3 (C2CD3))

Andere Bezeichnung: C2CD3

Hintergrund: C2CD3, a putative calcium-dependent lipid-binding protein, is an essential regulator of intracellular transduction of the Hedgehog signal (1). It is localized at the basal body of cilia, mediates calcium-dependent vesicular transport and/or recruitment of proteins and regulates cilium biogenesis by promoting the assembly of centriolar distal appendages critical for docking ciliary vesicles and recruiting other essential ciliogenic proteins (2,3). C2CD3 directly promotes centriole elongation and OFD1 acts as a negative regulator of C2CD3 (4,5).

Molekulargewicht: Predicted: 216, 259 kDa

Observed: 255 kDa

Gen-ID: 26005

NCBI Accession: NP_001273506

UniProt: Q4AC94