HOPX Antikörper (N-Term)

Produktnummer ABIN6992122

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HOPX in WB, ELISA, IF und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für HOPX Antikörper (N-Term) (ABIN6992122)

Target: HOPX (HOP Homeobox (HOPX))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOPX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-HOPX Antikörper

Bindungsspezifität: N-Term

Spezifität: HOPX antibody is human specific. At least three isoforms of HOPX are known to exist, this antibody will detect all three isoforms.

Aufreinigung: HOPX antibody is affinity chromatography purified via peptide column.

Immunogen: HOPX antibody was raised against a 16 amino acid peptide near the amino terminus of human HOPX. The immunogen is located within the first 50 amino acids of HOPX.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: HOPX antibody can be used for detection of HOPX by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: HOPX antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: HOPX antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu HOPX

Target: HOPX (HOP Homeobox (HOPX))

Andere Bezeichnung: HOPX

Hintergrund: HOPX is a small homeodomain protein that lacks normally conserved residues required for DNA binding (1). It is thought to act downstream of NKX2-5 and modulates serum response factor (SRF)-dependent cardiac-specific gene expression and cardiac development (1). HOPX also acts a tumor suppressor gene in multiple tumors and cancer cell lines (2,3). HOPX has been reported to regulate the proliferation/differentiation homeostasis in different cell types, including keratinocytes (4).

Molekulargewicht: Predicted: 12 kDa

Observed: 18 kDa

Gen-ID: 84525

NCBI Accession: NP_001138932

UniProt: Q9BPY8

Pathways: Regulation of Muscle Cell Differentiation