HOPX Antikörper (N-Term)

Produktnummer ABIN6992122

Produktdetails anti-HOPX Antikörper

Target: HOPX (HOP Homeobox (HOPX))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOPX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Spezifität: HOPX antibody is human specific. At least three isoforms of HOPX are known to exist, this antibody will detect all three isoforms.

Aufreinigung: HOPX antibody is affinity chromatography purified via peptide column.

Immunogen: HOPX antibody was raised against a 16 amino acid peptide near the amino terminus of human HOPX. The immunogen is located within the first 50 amino acids of HOPX.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: HOPX antibody can be used for detection of HOPX by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: HOPX antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: HOPX antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu HOPX

Target: HOPX (HOP Homeobox (HOPX))

Andere Bezeichnung: HOPX (HOPX Produkte)

Synonyme: CAMEO antikoerper, HOD antikoerper, HOP antikoerper, LAGY antikoerper, NECC1 antikoerper, OB1 antikoerper, SMAP31 antikoerper, TOTO antikoerper, 1110018K11Rik antikoerper, 1200015P04Rik antikoerper, 2300002F06Rik antikoerper, AI848177 antikoerper, AW490897 antikoerper, Cameo antikoerper, Hdop antikoerper, Hod antikoerper, Hop antikoerper, Ob1 antikoerper, Obl antikoerper, Toto antikoerper, GIIg15b antikoerper, HOPX antikoerper, hod antikoerper, hop antikoerper, ob1 antikoerper, lagy antikoerper, toto antikoerper, cameo antikoerper, necc1 antikoerper, smap31 antikoerper, MGC147344 antikoerper, HOP homeobox antikoerper, HOPX antikoerper, Hopx antikoerper, hopx antikoerper

Hintergrund: HOPX is a small homeodomain protein that lacks normally conserved residues required for DNA binding (1). It is thought to act downstream of NKX2-5 and modulates serum response factor (SRF)-dependent cardiac-specific gene expression and cardiac development (1). HOPX also acts a tumor suppressor gene in multiple tumors and cancer cell lines (2,3). HOPX has been reported to regulate the proliferation/differentiation homeostasis in different cell types, including keratinocytes (4).

Molekulargewicht: Predicted: 12 kDa

Observed: 18 kDa

Gen-ID: 84525

NCBI Accession: NP_001138932

UniProt: Q9BPY8

Pathways: Regulation of Muscle Cell Differentiation