SOX4 Antikörper (N-Term)

Produktnummer ABIN6992114

Der Kaninchen Polyklonal Anti-SOX4-Antikörper wurde für WB, ELISA, IHC (p) und IF validiert. Er ist geeignet, SOX4 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für SOX4 Antikörper (N-Term) (ABIN6992114)

Target: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-SOX4 Antikörper

Bindungsspezifität: N-Term

Spezifität: SOX4 antibody is human, mouse and rat reactive.

Aufreinigung: SOX4 antibody is affinity chromatography purified via peptide column.

Immunogen: SOX4 antibody was raised against a 16 amino acid peptide near the amino terminus of human SOX4. The immunogen is located within the first 50 amino acids of SOX4.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SOX4 antibody can be used for detection of SOX4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SOX4 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SOX4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu SOX4

Target: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Andere Bezeichnung: SOX4

Hintergrund: SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate (1,2). It may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin) (3). SOX4 contains one HMG box DNA-binding domain and may function in the apoptosis pathway leading to cell death. It has also been suggested to play a role in tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development (4,5).

Molekulargewicht: Predicted: 52 kDa

Observed: 520 kDa

Gen-ID: 6659

NCBI Accession: NP_003098

UniProt: Q06945