CTHRC1 Antikörper (N-Term)

Produktnummer ABIN6992108

Der Kaninchen Polyklonal anti-CTHRC1 Antikörper wird verwendet zum Nachweis von CTHRC1 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, ELISA, IHC (p) und IF.

Kurzübersicht für CTHRC1 Antikörper (N-Term) (ABIN6992108)

Target: CTHRC1 (Collagen Triple Helix Repeat Containing 1 (CTHRC1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTHRC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-CTHRC1 Antikörper

Bindungsspezifität: N-Term

Spezifität: CTHRC1 antibody is human, mouse and rat reactive. At least two isoforms of CTHRC1 are known to exist, this antibody will detect only the larger isoform.

Aufreinigung: CTHRC1 antibody is affinity chromatography purified via peptide column.

Immunogen: CTHRC1 antibody was raised against a 19 amino acid peptide near the amino terminus of human CTHRC1. The immunogen is located within the first 50 amino acids of CTHRC1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CTHRC1 antibody can be used for detection of CTHRC1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: CTHRC1 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: CTHRC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu CTHRC1

Target: CTHRC1 (Collagen Triple Helix Repeat Containing 1 (CTHRC1))

Andere Bezeichnung: CTHRC1

Hintergrund: The Collagen triple helix repeat-containing protein (CTHRC1) is a glycosylated, secreted protein that is transiently expressed in the arterial wall in response to injury where it is thought to contribute to vascular remodeling by inhibiting collagen expression and deposition and promoting cell migration (1). CTHRC1 is highly expressed multiple human cancers, including pancreatic cancer where it plays a significant role in the progression and metastasis of the disease by regulating migration and adhesion of tumors cells (2). CTHRC1 overexpression can also be used as an independent prognostic marker in gastric cancer (3). Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma (4).

Molekulargewicht: Predicted: 27 kDa

Observed: 27 kDa

Gen-ID: 115908

NCBI Accession: NP_612464

UniProt: Q96CG8

Pathways: Tube Formation