GJB2 Antikörper (AA 80-130)

Produktnummer ABIN6992084

Der Kaninchen Polyklonal Anti-GJB2-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, GJB2 in Proben von Human zu detektieren.

Kurzübersicht für GJB2 Antikörper (AA 80-130) (ABIN6992084)

Target: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GJB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GJB2 Antikörper

Bindungsspezifität: AA 80-130

Spezifität: GJB2 antibody is human specific.

Aufreinigung: GJB2 antibody is affinity chromatography purified via peptide column.

Immunogen: GJB2 antibody was raised against a 16 amino acid peptide near the center of human GJB2. The immunogen is located within amino acids 80 - 130 of GJB2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: GJB2 antibody can be used for detection of GJB2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: GJB2 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: GJB2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu GJB2

Target: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Andere Bezeichnung: GJB2

Hintergrund: The Gap junction beta-2 protein (GJB2), also known as Connexin 26, is member of the gap junction protein family which form structures that were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells (1). Mutations in the GJB2 gene are thought to be responsible for as much as 35-45 % of congenital sensorineural hearing loss in some populations (2). Other mutations in this gene have also been linked to a wide array of skin diseases (3).

Molekulargewicht: Predicted: 25 kDa

Observed: 26 kDa

Gen-ID: 2706

NCBI Accession: NP_003995

UniProt: P29033

Pathways: Sensory Perception of Sound, Cell-Cell Junction Organization