RHOG Antikörper (N-Term)

Produktnummer ABIN6992068

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RHOG in WB, ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für RHOG Antikörper (N-Term) (ABIN6992068)

Target: RHOG (Ras Homolog Family Member G (RHOG))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RHOG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RHOG Antikörper

Bindungsspezifität: AA 40-90, N-Term

Spezifität: RHOG antibody is human, mouse and rat reactive.

Aufreinigung: RHOG antibody is affinity chromatography purified via peptide column.

Immunogen: RHOG antibody was raised against a 15 amino acid peptide near the amino terminus of human RHOG. The immunogen is located within amino acids 40 - 90 of RHOG.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: RHOG antibody can be used for detection of RHOG by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: RHOG antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: RHOG antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu RHOG

Target: RHOG (Ras Homolog Family Member G (RHOG))

Andere Bezeichnung: RHOG

Hintergrund: The ras homolog family member G (RHOG), also known as rho-related GTP-binding protein, is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades (1). RHOG controls a pathway that requires the microtubule network and activates Rac1 and Cdc42Hs independently of their growth factor signaling pathway (2). RHOG is also involved in the transcriptional regulation of interferon-gamma and nuclear factor of activated T cells (NFAT) and the regulation of the actin skeleton in lymphocytes (3).

Molekulargewicht: Predicted: 21 kDa

Observed: 23 kDa

Gen-ID: 391

NCBI Accession: NP_001656

UniProt: P84095

Pathways: RTK Signalweg