CD55 Antikörper (C-Term)

Produktnummer ABIN6992050

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CD55 in WB, IF, ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD55 Antikörper (C-Term) (ABIN6992050)

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD55 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CD55 Antikörper

Bindungsspezifität: AA 360-410, C-Term

Spezifität: DAF antibody is human specific. At least two isoforms of DAF are known to exist, this antibody will only detect the longest isoform.

Aufreinigung: DAF antibody is affinity chromatography purified via peptide column.

Immunogen: DAF antibody was raised against an 18 amino acid peptide near the carboxy terminus of human DAF. The immunogen is located within amino acids 360 - 410 of DAF.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: DAF body can be used for detection of DAF by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: DAF antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: DAF antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu CD55

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Andere Bezeichnung: DAF

Hintergrund: The decay-accelerating factor (DAF), also known as CD55, is an integral membrane glycoprotein that is involved in the regulation of the complement cascade (1). DAF limits excessive complement activation by accelerating their decay following DAF binding, thereby disrupting the cascade and preventing damage to host cells (2). Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM) (3).

Molekulargewicht: Predicted: 48 kDa

Observed: 49 kDa

Gen-ID: 1604

NCBI Accession: NP_001108224

UniProt: P08174

Pathways: Komplementsystem, Regulation of Leukocyte Mediated Immunity