LIN54 Antikörper (C-Term)

Produktnummer ABIN6992048

Der Kaninchen Polyklonal Anti-LIN54-Antikörper wurde für WB, ELISA, ICC und IF validiert. Er ist geeignet, LIN54 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für LIN54 Antikörper (C-Term) (ABIN6992048)

Target: LIN54 (Lin-54 Homolog (LIN54))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIN54 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-LIN54 Antikörper

Bindungsspezifität: C-Term

Spezifität: LIN54 antibody is human, mouse, and rat reactive. Multiple isoforms of LIN54 are known to exist.

Aufreinigung: LIN54 antibody is affinity chromatography purified via peptide column.

Immunogen: LIN54 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human LIN54. The immunogen is located within the last 50 amino acids of LIN54.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: LIN54 antibody can be used for detection of LIN54 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: LIN54 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: LIN54 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu LIN54

Target: LIN54 (Lin-54 Homolog (LIN54))

Andere Bezeichnung: LIN54

Hintergrund: LIN54 is a component of the LIN, or DREAM, complex, an essential regulator of cell cycle genes. This complex functions as a transcriptional repressor by binding to promoters of E2F target genes that regulate the G1/S transition (1). LIN54 is required for cell cycle progression and can bind to the cdc2 promoter in a sequence-specific manner (2).

Molekulargewicht: Predicted: 88 kDa

Observed: 82 kDa

Gen-ID: 132660

NCBI Accession: NP_919258

UniProt: Q6MZP7

Pathways: Zellzyklus, Mitotic G1-G1/S Phases