HDAC6 Antikörper (C-Term)

Produktnummer ABIN6992036

Der Kaninchen Polyklonal Anti-HDAC6-Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, HDAC6 in Proben von Human und Maus zu detektieren.

Kurzübersicht für HDAC6 Antikörper (C-Term) (ABIN6992036)

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-HDAC6 Antikörper

Bindungsspezifität: C-Term

Spezifität: HDAC6 antibody is human and mouse reactive. Multiple isoforms of HDAC6 are known to exist. HDAC6 antibody is predicted to not cross-react with other members of the HDAC family.

Aufreinigung: HDAC6 antibody is affinity chromatography purified via peptide column.

Immunogen: HDAC6 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human HDAC6. The immunogen is located within the last 50 amino acids of HDAC6.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: HDAC6 body can be used for detection of HDAC6 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: HDAC6 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: HDAC6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu HDAC6

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Andere Bezeichnung: HDAC6

Hintergrund: The histone deacetylase (HDAC) family contains multiple members which are divided into four classes. Class II of the HDAC family comprises six members, HDAC4, 5, 6, 7, 9 and 10, each of which appear to have tissue-specific roles (1). HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other (2). HDAC6 has been shown to be part of the microtubule network and acts as a specific alpha-tubulin deacetylase, and has been suggested to be a potential therapeutic target in neurodegenerative disease (3).

Molekulargewicht: Predicted: 55 kDa

Observed: 32 kDa

Gen-ID: 10013

NCBI Accession: NP_006035

UniProt: Q9UBN7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling