GABARAPL2 Antikörper (C-Term)

Produktnummer ABIN6992033

Der Kaninchen Polyklonal Anti-GABARAPL2-Antikörper wurde für ELISA, WB, IF und IHC (p) validiert. Er ist geeignet, GABARAPL2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für GABARAPL2 Antikörper (C-Term) (ABIN6992033)

Target: GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABARAPL2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GABARAPL2 Antikörper

Bindungsspezifität: C-Term

Spezifität: GABARAPL2 antibody is human, mouse and rat reactive. Multiple isoforms of GABARAPL2 are known to exist.

Aufreinigung: GABARAPL2 antibody is affinity chromatography purified via peptide column.

Immunogen: GABARAPL2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human GABARAPL2. The immunogen is located within the last 50 amino acids of GABARAPL2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: GABARAPL2 antibody can be used for detection of GABARAPL2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse and rat samples and Immunofluorescence in mouse and rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: GABARAPL2 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: GABARAPL2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu GABARAPL2

Target: GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))

Andere Bezeichnung: GABARAPL2

Hintergrund: Gamma-aminobutyric acid (GABA) is the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing in the central nervous system (1). It has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC (2). GABARAPL2 (GABAA receptor-associated protein-like 2), also known as GATE16, was initially identified as a membrane transport modulator and is a mammalian ortholog to the autophagy protein ATG8 (3,4). It is thought that GABARAPL2 and other members of the ATG8 family act as scaffolds for assembly of the Unc-51 like kinase (ULK) complex in the formation of autophagosomes (5).

Molekulargewicht: Predicted: 13 kDa

Observed: 13 kDa

Gen-ID: 11345

NCBI Accession: NP_009216

UniProt: P60520

Pathways: Autophagie