NDST2 Antikörper (N-Term)

Produktnummer ABIN6992024

Produktdetails anti-NDST2 Antikörper

Target: NDST2 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 2 (NDST2))

Bindungsspezifität: AA 20-70, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDST2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Spezifität: NDST2 antibody is human, mouse and rat reactive. At least two isoforms of NDST2 are known to exist, this antibody will only detect the larger isoform. NDST2 antibody is predicted not to cross-react with other members of the NDST protein family.

Aufreinigung: NDST2 antibody is affinity chromatography purified via peptide column.

Immunogen: NDST2 antibody was raised against a 16 amino acid peptide near the amino terminus of human NDST2. The immunogen is located within amino acids 20 - 70 of NDST2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: NDST2 antibody can be used for detection of PDCL by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: NDST2 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: NDST2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu NDST2

Target: NDST2 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 2 (NDST2))

Andere Bezeichnung: NDST2 (NDST2 Produkte)

Synonyme: NDST1 antikoerper, HSST2 antikoerper, NST2 antikoerper, Mndns antikoerper, NDST-2 antikoerper, ndst2 antikoerper, N-deacetylase and N-sulfotransferase 2 antikoerper, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 antikoerper, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b antikoerper, NDST2 antikoerper, Ndst2 antikoerper, ndst2b antikoerper

Hintergrund: The N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 (NDST2) protein, also known as N-heparan sulfate sulfotransferase 2, and the highly related protein NDST1 have key roles in the sulfation of heparan sulfate proteoglycans, molecules that are present of cell surfaces and the extracellular matrix (1,2). NDST1 and NDST2 are dispensable for mesodermal differentiation into osteoblasts but necessary for induction of adipocytes and neural cells (3).

Molekulargewicht: Predicted: 97 kDa

Observed: 101 kDa

Gen-ID: 8509

NCBI Accession: NP_003626

UniProt: P52849

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Glycosaminoglycan Metabolic Process