IFIT1 Antikörper (C-Term)

Produktnummer ABIN6991993

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IFIT1 in WB, ELISA, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für IFIT1 Antikörper (C-Term) (ABIN6991993)

Target: IFIT1 (Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFIT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-IFIT1 Antikörper

Bindungsspezifität: AA 290-340, C-Term

Spezifität: IFIT1 antibody is human, mouse and rat reactive. At least three isoforms of IFIT1 are known to exist. This antibody is predicted to not cross-react with other members of the IFIT protein family.

Aufreinigung: IFIT1 antibody is affinity chromatography purified via peptide column.

Immunogen: IFIT1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IFIT1. The immunogen is located within amino acids 290 - 340 of IFIT1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IFIT1 antibody can be used for detection of IFIT1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: IFIT1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: IFIT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu IFIT1

Target: IFIT1 (Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1))

Andere Bezeichnung: IFIT1

Hintergrund: The interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) protein is a member of a family of tetratricopeptide repeat-containing proteins whose transcription is upregulated by interferons, virus infection, and molecular patterns such as dsRNA or lipopolysaccharides (1,2). These proteins have been suggested to induce anti-viral cellular activities in response to infection (2). Together with the interferon-induced transmembrane protein 1 (IFITM1), IFIT1 inhibits the replication of the Hepatitis C virus, suggesting that it may be useful in the development of therapeutic treatments (3).

Molekulargewicht: Predicted: 53 kDa

Observed: 53 kDa

Gen-ID: 3434

NCBI Accession: NP_001539

UniProt: P09914

Pathways: Hepatitis C