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alpha Tubulin Antikörper (N-Term)

TUBA1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6991939
  • Target Alle alpha Tubulin (TUBA1) Antikörper anzeigen
    alpha Tubulin (TUBA1)
    Bindungsspezifität
    • 16
    • 11
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 106
    • 80
    • 71
    • 22
    • 19
    • 16
    • 14
    • 12
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 57
    • 55
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 73
    • 51
    • 2
    Polyklonal
    Konjugat
    • 86
    • 11
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser alpha Tubulin Antikörper ist unkonjugiert
    Applikation
    • 97
    • 44
    • 38
    • 34
    • 34
    • 33
    • 26
    • 18
    • 7
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Spezifität
    Alpha-tubulin antibody is human, mouse and rat reactive.
    Aufreinigung
    Alpha-tubulin antibody is affinity chromatography purified via peptide column.
    Immunogen
    Alpha-tubulin antibody was raised against an 18 amino acid peptide near the amino terminus of human alpha-tubulin. The immunogen is located within the first 50 amino acids of Alpha-tubulin.
    Isotyp
    IgG
    Top Product
    Discover our top product TUBA1 Primärantikörper
  • Applikationshinweise
    Alpha-tubulin antibody can be used for detection of alpha-tubulin by Western blot at 0.25 - 0.5 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Alpha-tubulin antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    Alpha-tubulin antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target
    alpha Tubulin (TUBA1)
    Andere Bezeichnung
    Alpha-tubulin (TUBA1 Produkte)
    Synonyme
    Tuba1 antikoerper, K-ALPHA-1 antikoerper, Tuba-1 antikoerper, cb944 antikoerper, fb22g06 antikoerper, tuba1 antikoerper, wu:fb22g06 antikoerper, Calpha1 antikoerper, tubulin, alpha 1A antikoerper, tubulin alpha 1b antikoerper, tubulin, alpha 1b antikoerper, tubulin, alpha 1B antikoerper, Tuba1a antikoerper, TUBA1B antikoerper, tuba1b antikoerper, Tuba1b antikoerper
    Hintergrund
    Alpha-tubulin belongs to the tubulin superfamily, which is composed of six distinct families. Along with beta-tubulins, alpha-tubulins are the major components of microtubules. These microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Alpha- and beta-tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter (reviewed in 1). Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha-tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase (2). Another post-translational modification of detyrosinated alpha-tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle (3). Like GAPDH and ?-Actin, this antibody makes an excellent loading control in immunoblots.
    Molekulargewicht
    Predicted: 50 kDa

    Observed: 45 kDa
    Gen-ID
    7278
    NCBI Accession
    NP_005992
    UniProt
    Q13748
    Pathways
    Microtubule Dynamics
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