CXCL12 Antikörper

Produktnummer ABIN6991936

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CXCL12 in WB, ELISA und ICC. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für CXCL12 Antikörper (ABIN6991936)

Target: CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCL12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Produktdetails anti-CXCL12 Antikörper

Spezifität: CXCL12 antibody is human and mouse reactive. Multiple isoforms of CXCL12 are known to exist.

Aufreinigung: CXCL12 antibody is affinity chromatography purified via peptide column.

Immunogen: CXCL12 antibody was raised against a 16 amino acid peptide near the center of human CXCL12 . The immunogen is located within the last 50 amino acids of CXCL12.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CXCL12 antibody can be used for detection of CXCL12 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: CXCL12 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: CXCL12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu CXCL12

Target: CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

Andere Bezeichnung: CXCL12

Hintergrund: The CXCL12 protein, also known as SDF1, is a stromal cell-derived alpha chemokine member of the intercrine family. CXCL12 functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4 (CXCR4) and CXCR7, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis (reviewed in 1). Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections (2).

Molekulargewicht: Predicted: 15 kDa

Observed: 18 kDa

Gen-ID: 6387

NCBI Accession: NP_001171605

UniProt: P48061

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling