IL1RL2 Antikörper (AA 260-310)

Produktnummer ABIN6991913

Der Kaninchen Polyklonal Anti-IL1RL2-Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, IL1RL2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für IL1RL2 Antikörper (AA 260-310) (ABIN6991913)

Target: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL1RL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-IL1RL2 Antikörper

Bindungsspezifität: AA 260-310

Spezifität: IL-1RL2 antibody is human, mouse and rat reactive. At least three isoforms of IL-1RL2 are known to exist, this antibody will detect all three isoforms. IL-1RL2 antibody is predicted to not cross-react with IL-1R or IL-1RL1.

Aufreinigung: IL-1RL2 antibody is affinity chromatography purified via peptide column.

Immunogen: IL-1RL2 antibody was raised against a 16 amino acid peptide near the center of human IL-1RL2. The immunogen is located within amino acids 260 - 310 of IL-1RL2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IL-1RL2 antibody can be used for detection of IL-1RL2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: IL-1RL2 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: IL-1RL2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu IL1RL2

Target: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Andere Bezeichnung: IL-1RL2

Hintergrund: IL-1RL2 is a member of the interleukin 1 receptor family, but it is incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity (1). Together with IL-1RAcP, it can bind members of the IL-36 cytokine family, leading to activation of the NF-kappaB pathway (2). IL-1RL2 can also bind to IL-1F10, resulting in a decreased product of Th17 cytokines in response to immunological or LPS challenge, suggesting that one potential role of IL-1RL2 may be to modulate the immune and inflammation response (3).

Molekulargewicht: Predicted: 61 kDa

Observed: 55 kDa

Gen-ID: 8808

NCBI Accession: NP_003845

UniProt: Q9HB29