IL28B Antikörper (AA 120-170)

Produktnummer ABIN6991905

Der Kaninchen Polyklonal anti-IL28B Antikörper (ABIN6991905) detektiert spezifisch IL28B in WB, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IL28B Antikörper (AA 120-170) (ABIN6991905)

Target: IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL28B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-IL28B Antikörper

Bindungsspezifität: AA 120-170

Spezifität: IL-28B antibody is human specific. IL-28B antibody may cross-react with IL-28A and IL-29.

Aufreinigung: IL-28B Antibody is affinity chromatography purified via peptide column.

Immunogen: IL-28B antibody was raised against a 17 amino acid peptide near the center of human IL-28B. The immunogen is located within amino acids 120 - 170 of IL-28B .

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IL-28B antibody can be used for detection of IL-28B by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: IL-28B Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: IL-28B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu IL28B

Target: IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))

Andere Bezeichnung: IL-28B

Hintergrund: Interleukin 28 (IL-28B), also known as interferon lambda 3, is cytokine distantly related to type I interferons and the IL-10 family (1). The IL-28B gene and the closely related cytokine genes IL-28A and IL-29 form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection and can induce anti-viral activity (2,3). All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor-beta (IL10RB) and interleukin 28 receptor- alpha (IL28RA) (1).

Molekulargewicht: Predicted: 20 kDa

Observed: 16kDa

Gen-ID: 282617

NCBI Accession: NP_742151

UniProt: Q8IZI9