IL28B Antikörper (N-Term)

Produktnummer ABIN1539309

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-IL28B Antikörper (Klon RB36625) (ABIN1539309) detektiert spezifisch IL28B in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IL28B Antikörper (N-Term) (ABIN1539309)

Target: IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL28B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB36625

Produktdetails anti-IL28B Antikörper

Bindungsspezifität: AA 34-63, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IL28B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-63 amino acids from the N-terminal region of human IL28B.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: IL28B Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Referenzen für anti-IL28B Antikörper (ABIN1539309)

Ferraris, Chandra, Panigrahi, Aboulnasr, Chava, Kurt, Pawlotsky, Wilkens, Osterlund, Hartmann, Balart, Wu, Dash: "Cellular Mechanism for Impaired Hepatitis C Virus Clearance by Interferon Associated with IFNL3 Gene Polymorphisms Relates to Intrahepatic Interferon-λ Expression." in: The American journal of pathology, Vol. 186, Issue 4, pp. 938-51, (2016) (PubMed).

Details zu IL28B

Target: IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))

Andere Bezeichnung: IL28B

Hintergrund: This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).

Molekulargewicht: 21706

Gen-ID: 282617

NCBI Accession: NP_742151

UniProt: Q8IZI9