Der Kaninchen Polyklonal anti-CEACAM5 Antikörper wird verwendet zum Nachweis von CEACAM5 in Proben von Human und Ratte. Er wurde validiert für WB und ELISA.
CEACAM5 antibody is human, mouse and rat reactive. CEACAM5 antibody is predicted to not cross-react with other CEACAM protein family members.
Aufreinigung
CEACAM5 Antibody is affinity chromatography purified via peptide column.
Immunogen
CEACAM5 antibody was raised against a 15 amino acid peptide near the center of human CEACAM5. The immunogen is located within amino acids 310 - 360 of CEACAM5 .
CEACAM5 is a member of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily (1,2). CEACAM proteins are involved in cell-cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation (2). CEACAM5 has been shown to be overexpressed in a majority of carcinomas and has been suggested to be a intercellular adhesion molecule involved in cancer invasion and metastasis (3).