Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
Spezifität
NCBP1 antibody is human, mouse and rat reactive. At least two isoforms of NCBP1 are known to exist, this antibody will detect both isoforms of NCBP1.
Aufreinigung
NCBP1 Antibody is affinity chromatography purified via peptide column.
Immunogen
NCBP1 antibody was raised against a 17 amino acid peptide near the center of human NCBP1. The immunogen is located within amino acids 420 - 470 of NCBP1.
CBP80 antikoerper, CG7035 antikoerper, Dmel\\CG7035 antikoerper, EG:84H4.3 antikoerper, ncbp antikoerper, sto1 antikoerper, cbp80 antikoerper, AU014645 antikoerper, AW538051 antikoerper, NCBP antikoerper, Sto1 antikoerper, ncbp1 antikoerper, ABA HYPERSENSITIVE 1 antikoerper, ATCBP80 antikoerper, CAP-BINDING PROTEIN 80 antikoerper, ENS antikoerper, ENSALADA antikoerper, NUCLEAR CAP-BINDING PROTEIN CBP80 antikoerper, T10F5.8 antikoerper, T10F5_8 antikoerper, cap binding protein 80 antikoerper, nuclear cap binding protein subunit 1 antikoerper, nuclear cap binding protein subunit 1 S homeolog antikoerper, nuclear cap binding protein subunit 1, 80kDa antikoerper, nuclear cap binding protein subunit 1 L homeolog antikoerper, ARM repeat superfamily protein antikoerper, Nuclear cap-binding protein subunit 1-A antikoerper, Nuclear cap-binding protein subunit 1 antikoerper, Cbp80 antikoerper, ncbp1 antikoerper, ncbp1.S antikoerper, NCBP1 antikoerper, Ncbp1 antikoerper, ncbp1.L antikoerper, ABH1 antikoerper, nbp1a antikoerper, ncbp-1 antikoerper
Hintergrund
NCBP1 Antibody: NCBP1, also known as CBP80, is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. NCBP1 promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay (1,2). Recent evidence has shown that cellular-cap-binding proteins such as NCBP1 associate with influenza virus mRNAs, suggesting that these viral mRNAs may follow the normal cellular pathways for splicing, nuclear export, and translation (3).