GOLGA5 Antikörper (C-Term)

Produktnummer ABIN6991873

Produktdetails anti-GOLGA5 Antikörper

Target: GOLGA5 (Golgin A5 (GOLGA5))

Bindungsspezifität: AA 540-590, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GOLGA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: GOLGA5 antibody is human, mouse and rat reactive. Two isoforms of GOLGA5 exist due to alternative splicing events.

Aufreinigung: GOLGA5 Antibody is affinity chromatography purified via peptide column.

Immunogen: GOLGA5 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human GOLGA5. The immunogen is located within amino acids 540 - 590 of GOLGA5.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: GOLGA5 antibody can be used for detection of GOLGA5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: GOLGA5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: GOLGA5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu GOLGA5

Target: GOLGA5 (Golgin A5 (GOLGA5))

Andere Bezeichnung: GOLGA5 (GOLGA5 Produkte)

Synonyme: GOLIM5 antikoerper, RFG5 antikoerper, ret-II antikoerper, golim5 antikoerper, ret-ii antikoerper, rfg5 antikoerper, Ret-II antikoerper, im:7153094 antikoerper, sb:cb898 antikoerper, wu:fd50h11 antikoerper, zgc:66400 antikoerper, golgin A5 antikoerper, golgin A5 L homeolog antikoerper, golgi autoantigen, golgin subfamily a, 5 antikoerper, GOLGA5 antikoerper, golga5.L antikoerper, golga5 antikoerper, Golga5 antikoerper

Hintergrund: GOLGA5 Antibody: GOLGA5 (Golgi autoantigen, subfamily A, member 5), also known as GOLGA84, RFG5 (RET-fused gene 5 protein) or GOLIM5, is a ubiquitously expressed single-pass type II coiled-coil membrane protein that is involved in maintaining Golgi structure (1). It is localized to the Golgi apparatus and predominantly found on membranes at the cis side of the Golgi stack (1,2). As a mitotic phosphoprotein, GOLGA5 binds to active Rab 1 and associates with CASP (an isoform of CDP) in a golgin-tethering complex that is believed to play a role in intra-Golgi retrograde transport (3,4). Defects in GOLGA5 are a cause of thyroid papillary carcinoma (TPC) (5).

Molekulargewicht: Predicted: 64, 80 kDa

Observed: 65, 78 kDa

Gen-ID: 9950

NCBI Accession: NP_005104

UniProt: Q8TBA6