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SNRPE Antikörper (AA 330-380)

Dieses Anti-SNRPE-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SNRPE in WB, ELISA, IF und IHC (p). Geeignet für Human und Maus.
Produktnummer ABIN6991869

Kurzübersicht für SNRPE Antikörper (AA 330-380) (ABIN6991869)

Target

Alle SNRPE Antikörper anzeigen
SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))

Reaktivität

  • 67
  • 50
  • 48
  • 6
  • 5
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Human, Maus

Wirt

  • 82
  • 1
Kaninchen

Klonalität

  • 83
Polyklonal

Konjugat

  • 29
  • 7
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser SNRPE Antikörper ist unkonjugiert

Applikation

  • 30
  • 30
  • 27
  • 25
  • 13
  • 12
  • 10
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 15
    • 15
    • 9
    • 8
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 330-380

    Spezifität

    This antibody will not cross-react with C-raf.

    Aufreinigung

    B-raf Antibody is affinity chromatography purified via peptide column.

    Immunogen

    Anti-B-raf antibody was raised against a peptide corresponding to 19 amino acids near the center of human B-raf. The immunogen is located within amino acids 330 - 380 of B-raf.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 0.5-2 μ,g/mL, IHC: 2.5 μ,g/mL, IF: 20 μ,g/mL.

    Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    B-raf Antibody is supplied in PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,4 °C

    Informationen zur Lagerung

    B-raf antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target

    SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))

    Andere Bezeichnung

    B-raf

    Hintergrund

    B-raf Antibody: B-raf belongs to the raf/mil family of serine/threonine protein kinases and plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. The Ras/Raf/MEK/ERK and Ras/PI3K/PTEN/Akt pathways interact with each other to regulate growth and in some cases tumorigenesis. Mutations in B-raf have been associated with several cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung, leading to speculation on the possibility of B-raf as a therapeutic target for treating cancers. Mutations in this gene have also been associated with cardiofaciocutaneous syndrome (CFCS), a disease characterized by heart defects, mental retardation and a distinctive facial appearance.

    Molekulargewicht

    Predicted: 94kD

    Observed: 94 kD kDa

    Gen-ID

    673

    UniProt

    P15056

    Pathways

    Ribonucleoprotein Complex Subunit Organization, Hepatitis C
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