GABARAP Antikörper (N-Term)

Produktnummer ABIN6991865

Der Kaninchen Polyklonal anti-GABARAP Antikörper wird verwendet zum Nachweis von GABARAP in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IF und IHC (p).

Kurzübersicht für GABARAP Antikörper (N-Term) (ABIN6991865)

Target: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABARAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GABARAP Antikörper

Bindungsspezifität: N-Term

Spezifität: Multiple isoforms of GABARAP exist due to alternative splicing events.

Aufreinigung: GABARAP Antibody is affinity chromatography purified via peptide column.

Immunogen: GABARAP antibody was raised against a 19 amino acid peptide near the amino terminus of human GABARAP. The immunogen is located within the first 50 amino acids of GABARAP.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: GABARAP antibody can be used for detection of GABARAP by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: GABARAP Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: GABARAP antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu GABARAP

Target: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Andere Bezeichnung: GABARAP

Hintergrund: GABARAP Antibody: Gamma-aminobutyric acid (GABA) is the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing in the central nervous system. It has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. GABARAP (GABAA receptor-associated protein) links GABAA receptors to the cytoskeleton and may play a role in intracellular transport of GABAA receptors and its interaction with the cytoskeleton. GABARAP belongs to the MAP1 or ATG8 like family and recent studies show that MAPK15/ERK8 is acting through interaction with ATG8 family proteins to regulate autophagy.

Molekulargewicht: Predicted: 13kDa

Observed: 15 kDa

Gen-ID: 11337

NCBI Accession: NP_009209

UniProt: O95166

Pathways: Autophagie