CD59 Antikörper (N-Term)

Produktnummer ABIN6991822

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CD59 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für CD59 Antikörper (N-Term) (ABIN6991822)

Target: CD59

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD59 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CD59 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: CD59 Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal CD59 antibody was raised against a 14 amino acid peptide near the amino terminus of human CD59. The immunogen is located within the first 50 amino acids of CD59.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CD59 antibody can be used for detection of CD59 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: CD59 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: CD59 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu CD59

Target: CD59

Andere Bezeichnung: CD59

Hintergrund: CD59 Antibody: The complement regulatory protein CD59 is a cell surface glycoprotein that regulates complement-mediated cell lysis and is involved in lymphocyte signal transduction. CD59 is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. CD59 also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and ultimately cerebral infarction.

Molekulargewicht: 14 kDa

Gen-ID: 966

NCBI Accession: NP_000602

UniProt: P13987

Pathways: Komplementsystem