MECR Antikörper (C-Term)

Produktnummer ABIN6991794

Dieses Anti-MECR-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MECR in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für MECR Antikörper (C-Term) (ABIN6991794)

Target: MECR (Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MECR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MECR Antikörper

Bindungsspezifität: AA 300-350, C-Term

Spezifität: At least two isoforms of MECR are known to exist, this antibody will detect both isoforms.

Aufreinigung: MECR Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal MECR antibody was raised against a 15 amino acid peptide near the carboxy terminus of human MECR. The immunogen is located within amino acids 300 - 350 of MECR.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: MECR antibody can be used for detection of MECR by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human, mouse, and rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: MECR Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: MECR antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu MECR

Target: MECR (Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR))

Andere Bezeichnung: MECR

Hintergrund: MECR Antibody: The mitochondrial trans-2-enoyl-CoA reductase (MECR), was initially identified as nuclear receptor-binding factor 1 (NRBF1), which can interact with a multitude of nuclear hormone receptors in the presence of the respective ligands. MECR has been shown to be part of the mitochondrial fatty acid synthesis (FAS II) system and to catalyze the NAPDH-dependent reduction of 2-enoyl thioesters, generating saturated acyl-groups. Overexpression of this gene in transgenic mice can lead to cardiac abnormalities, suggesting that inappropriate expression of genes of FAS II can result in the development of hereditary cardiomyopathy.

Molekulargewicht: Predicted: 41 kDa

Gen-ID: 51102

NCBI Accession: NP_057095

UniProt: Q9BV79