TWEAK Antikörper

Produktnummer ABIN6991749

Dieses Anti-TWEAK-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TWEAK in WB, ELISA, IF und IHC (p). Geeignet für Human und Maus.

Kurzübersicht für TWEAK Antikörper (ABIN6991749)

Target: TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TWEAK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TWEAK Antikörper

Aufreinigung: TWEAK Antibody is Protein A-purified.

Immunogen: Anti-TWEAK antibody was raised against recombinant human TWEAK protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 0.5-4 μ,g/mL, IHC: 5-10 μ,g/mL, IF: 20 μ,g/mL.

Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry in human and mouse samples, Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TWEAK Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TWEAK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TWEAK

Target: TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))

Andere Bezeichnung: TWEAK

Hintergrund: TWEAK Antibody: TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane. TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis, induction of inflammatory cytokines, in addition to stimulation of apoptosis. The TWEAK signal transduction pathway has not been well established but it appears to signal via TweakR/Fn14 in a manner similar to that described for other TNFSF members that bind receptors lacking death domains.

Molekulargewicht: Predicted: 27 and 36 kD

Observed: 27 and 36 kD kDa

Gen-ID: 8742

NCBI Accession: NP_003800

UniProt: O43508

Pathways: Apoptose