KCP Antikörper (C-Term)

Produktnummer ABIN6991728

Dieses Anti-KCP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KCP in WB und ELISA. Geeignet für Human, Ratte und Maus.

Kurzübersicht für KCP Antikörper (C-Term) (ABIN6991728)

Target: KCP (Kielin/Chordin-Like Protein (KCP))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-KCP Antikörper

Bindungsspezifität: AA 1320-1370, C-Term

Spezifität: At least two isoforms of CRIM2 are known to exist, this antibody will only detect the larger isoform. CRIM2 antibody is predicted to not cross-react with CRIM1.

Aufreinigung: CRIM2 Antibody is affinity chromatography purified via peptide column.

Immunogen: CRIM2 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human CRIM2. The immunogen is located within amino acids 1320 - 1370 of CRIM2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CRIM2 antibody can be used for detection of CRIM2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: CRIM2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: CRIM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu KCP

Target: KCP (Kielin/Chordin-Like Protein (KCP))

Andere Bezeichnung: CRIM2

Hintergrund: CRIM2 Antibody: CRIM2, also known as Kielin/chordin-like protein (KCP), is a novel enhancer of BMP signaling. It binds to BMP7, a morphogen that is important for kidney development and part of the kidney's physiological response to repair of acute kidney injury, enhancing its binding to its receptor. Because of this, CRIM2 has been suggested as a potential antifibrotic therapy in acute and chronic kidney injury. CRIM2 can also interact directly with either activin or TGF-β,1, suppressing activin- and TGF-β,1-dependent transcription.

Gen-ID: 375616

NCBI Accession: NP_001129386

UniProt: Q6ZWJ8