KCP Antikörper (C-Term)

Produktnummer ABIN1449940

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch KCP in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für KCP Antikörper (C-Term) (ABIN1449940)

Target: KCP (Kielin/Chordin-Like Protein (KCP))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-KCP Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid synthetic peptide near the carboxy terminus of Human CRIM2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu KCP

Target: KCP (Kielin/Chordin-Like Protein (KCP))

Andere Bezeichnung: CRIM2

Hintergrund: CRIM2, also known as Kielin/chordin-like protein (KCP), is a novel enhancer of BMP signaling. It binds to BMP7, a morphogen that is important for kidney development and part of the kidney's physiological response to repair of acute kidney injury, enhancing its binding to its receptor. Because of this, CRIM2 has been suggested as a potential antifibrotic therapy in acute and chronic kidney injury. CRIM2 can also interact directly with either activin or TGF-beta1, suppressing activin- and TGF-beta1-dependent transcription.Synonyms: CRIM-2, Cysteine-rich motor neuron 2 protein, KCP1, NET67, kielin/chordin-like protein

Gen-ID: 375616

NCBI Accession: NP_001129386