ZFYVE21 Antikörper (N-Term)
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- Target Alle ZFYVE21 Antikörper anzeigen
- ZFYVE21 (Zinc Finger, FYVE Domain Containing 21 (ZFYVE21))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ZFYVE21 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Spezifität
- At least two isoforms of ZF21 are known to exist, this antibody will detect both isoforms.
- Aufreinigung
- ZF21 Antibody is affinity chromatography purified via peptide column.
- Immunogen
- ZF21 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ZF21. The immunogen is located within the first 50 amino acids of ZF21.
- Isotyp
- IgG
- Top Product
- Discover our top product ZFYVE21 Primärantikörper
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- Applikationshinweise
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ZF21 antibody can be used for detection of ZF21 by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- ZF21 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,4 °C
- Informationen zur Lagerung
- ZF21 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- ZFYVE21 (Zinc Finger, FYVE Domain Containing 21 (ZFYVE21))
- Andere Bezeichnung
- ZF21 (ZFYVE21 Produkte)
- Hintergrund
- ZF21 Antibody: ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.
- Gen-ID
- 79038
- NCBI Accession
- NP_001185882
- UniProt
- Q9BQ24
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