ZFYVE21 Antikörper (N-Term)

Produktnummer ABIN1449943

Produktdetails anti-ZFYVE21 Antikörper

Target: ZFYVE21 (Zinc Finger, FYVE Domain Containing 21 (ZFYVE21))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZFYVE21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid synthetic peptide near the amino terminus of Human ZF21

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ZFYVE21

Target: ZFYVE21 (Zinc Finger, FYVE Domain Containing 21 (ZFYVE21))

Andere Bezeichnung: ZFYVE21 (ZFYVE21 Produkte)

Synonyme: ZF21 antikoerper, 1110013H04Rik antikoerper, AW558780 antikoerper, C85416 antikoerper, zinc finger FYVE-type containing 21 antikoerper, zinc finger, FYVE domain containing 21 antikoerper, ZFYVE21 antikoerper, Zfyve21 antikoerper

Hintergrund: ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.Synonyms: Zinc finger FYVE domain-containing protein 21

Gen-ID: 79038

NCBI Accession: NP_001185882